Superiority of LC- MS3- Over LC-MRM Approach Regarding Quantification of Amantadine along with Applying its Utilization in Therapeutic Amantadine Monitoring in Human Plasma.
Amantadine hydrochloride (C10H17N HCL; Figure 1) [alias tricyclic-[3.3.1.13.7]decane-1-amine) rep resents a synthetic amine belonging to the amantadine class.It gets obtained from amantadine which targets the M2 ion channel which is basically used in the form of antiviral treatment. Amantadine (AMT) received ecommendation from the Food along with Drug administration (FAO) in2008 regarding utilization For Parkinson’s disease along with Multiple Sclerosis (MS) [1].